1. in any way; thoroughly全然地;在各方面
I don't agree with you at all. 我完全不同意你的看法。
There was nothing to worry about at all. 完全沒有什麼可擔心的。
2. in the least;to the least extent or degree任何;最輕程度地
Do you feel ill at all?你感到有任何不適嗎?
3. for any reason究竟
Do you know at all?你究竟知道不知道?