1. take the management of;become responsible for 負責
Professor Smith takes charge of the literature class. 史密斯教授負責文學班。
The secretary took charge of the matter until her boss returned. 秘書負責這件事直到老板回來為止。
She offered to take charge of all the arrangements for the conference. 她主動提出來負責會議的一切安排。
2. assume control of控制
When the fire started,the police and firemen quickly took charge of the situation. 著火時,警察以及消防隊員很快就控制了火勢。