estrange, alienate, alien, disaffect -- (arouse hostility or indifference in where there had formerly been love, affection, or friendliness; "She alienated her friends when she became fanatically religious")
alien, alienate -- (transfer property or ownership; "The will aliened the property to the heirs")
alienate -- (make withdrawn or isolated or emotionally dissociated; "the boring work alienated his employees")