abandon, forsake, desolate, desert -- (leave someone who needs or counts on you; leave in the lurch; "The mother deserted her children")
depopulate, desolate -- (reduce in population; "The epidemic depopulated the countryside")
lay waste to, waste, devastate, desolate, ravage, scourge -- (cause extensive destruction or ruin utterly; "The enemy lay waste to the countryside after the invasion")
Overview of adj desolate
The adj desolate has 2 senses
bare, barren, bleak, desolate, stark -- (providing no shelter or sustenance; "bare rocky hills"; "barren lands"; "the bleak treeless regions of the high Andes"; "the desolate surface of the moon"; "a stark landscape")
desolate -- (crushed by grief; "depressed and desolate of soul"; "a low desolate wail")