tire, pall, weary, fatigue, jade -- (lose interest or become bored with something or somebody; "I'm so tired of your mother and her complaints about my food")
exhausted, dog-tired, fagged, fatigued, played out, spent, washed-out, worn-out, worn out -- (drained of energy or effectiveness; extremely tired; completely exhausted; "the day's shopping left her exhausted"; "he went to bed dog-tired"; "was fagged and sweaty"; "the trembling of his played out limbs"; "felt completely washed-out"; "only worn-out horses and cattle"; "you look worn out")