operate, run -- (direct or control; projects, businesses, etc.; "She is running a relief operation in the Sudan")
function, work, operate, go, run -- (perform as expected when applied; "The washing machine won't go unless it's plugged in"; "Does this old car still run well?"; "This old radio doesn't work anymore")
operate, control -- (handle and cause to function; "do not operate machinery after imbibing alcohol"; "control the lever")
manoeuver, maneuver, manoeuvre, operate -- (perform a movement in military or naval tactics in order to secure an advantage in attack or defense)
operate -- (happen; "What is going on in the minds of the people?")
engage, mesh, lock, operate -- (keep engaged; "engaged the gears")
operate on, operate -- (perform surgery on; "The doctors operated on the patient but failed to save his life")
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