sorrow -- (an emotion of great sadness associated with loss or bereavement; "he tried to express his sorrow at her loss")
sorrow, regret, rue, ruefulness -- (sadness associated with some wrong done or some disappointment; "he drank to drown his sorrows"; "he wrote a note expressing his regret"; "to his rue, the error cost him the game")
grief, sorrow -- (something that causes great unhappiness; "her death was a great grief to John")
sadness, sorrow, sorrowfulness -- (the state of being sad; "she tired of his perpetual sadness")